Understanding of tolerance in TRAIL-induced apoptosis and cancelation of its machinery by α-mangostin, a xanthone derivative
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چکیده
منابع مشابه
Understanding of tolerance in TRAIL-induced apoptosis and cancelation of its machinery by α-mangostin, a xanthone derivative
Tumor necrosis-factor (TNF)-related apoptosis-inducing ligand (TRAIL) is a member of the TNF-superfamily that selectively induces apoptosis through death receptors (DRs) 4 and/or 5 in cancer cells. These receptors are expressed on the cancer cell surface, without affecting normal cells. Unfortunately, many clinical studies have shown that cancer cells acquire TRAIL-resistance and finally avoid ...
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Five xanthone derivatives and one flavanol were isolated from the dichloromethane extract of Garcinia mangostana. Dichloromethane, ethyl acetate extract and the major xanthone (α-mangostin) were evaluated in vitro against erythrocytic schizonts of Plasmodium falciparum, intracellular amastigotes of Leishmania infantum and Trypanosoma cruzi and free trypomastigotes of T. brucei. The major consti...
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In recent decades, there has been increasing interest in the use of herbs to maintain human health, many growing in the Southern and Eastern Asian countries. One example, pericarps of Garcinia mangostana (GM), called mangosteen, have been in use for hundreds of years as a traditional herbal medicine for a variety of purposes, including treatment of skin infections and wounds (Mahabusarakam, 198...
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هدف از این تحقیق بررسی انتقال صور خیال هملت در دو ترجمه ی فارسی آن از نظر فرمالیستی بود. برای بدست آوردن داده-های مورد نیاز، 130 نمونه استعاره، مجاز، ایهام، کنایه و پارادوکس در متن اصلی مشخص شده و سپس بر اساس مدل نیومارک (1998) برای ترجمه ی استعاره یا بطور کلی زبان مجاز با معادل های فارسی شان مقایسه گردیدند. این تحقیق بر آن بود تا روش های استفاده شده برای ترجمه هر کدام از انواع زبان مجاز ذکر شد...
15 صفحه اولInvolvement of NF-κB and HSP70 signaling pathways in the apoptosis of MDA-MB-231 cells induced by a prenylated xanthone compound, α-mangostin, from Cratoxylum arborescens [Retraction]
[This retracts the article on p. 1629 in vol. 8.].
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ژورنال
عنوان ژورنال: Oncotarget
سال: 2015
ISSN: 1949-2553
DOI: 10.18632/oncotarget.4558